Characterization of a Suppressive Cis-acting Element in the Epstein–Barr Virus LMP1 Promoter
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چکیده
منابع مشابه
Characterization of a Suppressive Cis-acting Element in the Epstein–Barr Virus LMP1 Promoter
Latent membrane protein 1 (LMP1) is a major oncogene encoded by Epstein-Barr virus (EBV) and is essential for immortalization of B cells by the virus. Previous studies suggested that several transcription factors, such as PU.1, RBP-Jκ, NFκB, EBF1, AP-2 and STAT, are involved in LMP1 induction; however, the means by which the oncogene is negatively regulated remains unclear. Here, we introduced ...
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ژورنال
عنوان ژورنال: Frontiers in Microbiology
سال: 2017
ISSN: 1664-302X
DOI: 10.3389/fmicb.2017.02302